H-9 hydrochloride

CAS No. 116970-50-4

H-9 hydrochloride( —— )

Catalog No. M21838 CAS No. 116970-50-4

H-9 hydrochloride inhibits PKA (Ki=1.9 μM), PKC (Ki=18 μM; cGKI (PKG) =0.87 μM; MLCK=70 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    H-9 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    H-9 hydrochloride inhibits PKA (Ki=1.9 μM), PKC (Ki=18 μM; cGKI (PKG) =0.87 μM; MLCK=70 μM).
  • Description
    H-9 hydrochloride inhibits PKA (Ki=1.9 μM), PKC (Ki=18 μM; cGKI (PKG) =0.87 μM; MLCK=70 μM). It has shown to dramatically reduce the GABA response of GABAA currents in retinal rod bipolar cells as well as inhibit smooth muscle cell relaxation induced by cGRP. H-9 dihydrochloride has also been used for purification of protein kinases in ligand affinity chromatography.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    cGKI
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    116970-50-4
  • Formula Weight
    287.77
  • Molecular Formula
    C11H13N3O2S?HCl
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCN.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wolf, M., et al. 1985. J. Biol. Chem. 260: 15718-15722. PMID: 4066694 2. Inagaki, M., et al. 1985. J. Biol. Chem. 260: 2922-2925. PMID: 2982842 3. Gillette, M.A., et al. 1996. J. Neurophysiol. 76: 3070-3086. PMID: 8930256
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