H-9 hydrochloride

Research use only, not for human use.

H-9 hydrochloride is a potent and competitive inhibitor of protein kinase C, cAMP-dependent protein kinase, and cGMP.

H-9 hydrochloride inhibits PKA (Ki=1.9 μM), PKC (Ki=18 μM; cGKI (PKG) =0.87 μM; MLCK=70 μM). It has shown to dramatically reduce the GABA response of GABAA currents in retinal rod bipolar cells as well as inhibit smooth muscle cell relaxation induced by cGRP. H-9 dihydrochloride has also been used for purification of protein kinases in ligand affinity chromatography.

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Others

Other Targets

cGKI

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116970-50-4

287.77

C11H13N3O2SHCl

>98% (HPLC)

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C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCN.Cl

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(-20℃)

With Ice Pack

≥ 2 years